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Cornell University

Eric Siggia Group

Publications

Publications from 1970 - 2009

Additional Publications

2023

A geometrical perspective on development

Raju A, Siggia ED. A geometrical perspective on development. Development Growth and Differentiation. 2023;.

2022

Mechanisms underlying WNT-mediated priming of human embryonic stem cells

Yoney A, Bai L, Brivanlou AH, Siggia ED. Mechanisms underlying WNT-mediated priming of human embryonic stem cells. Development (Cambridge). 2022;149(20).

Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models

Metzger JJ, Pereda C, Adhikari A, Haremaki T, Galgoczi S, Siggia ED, et al. Deep-learning analysis of micropattern-based organoids enables high-throughput drug screening of Huntington's disease models. Cell Reports Methods. 2022;2(9).

In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells

Simunovic M, Siggia ED, Brivanlou AH. In vitro attachment and symmetry breaking of a human embryo model assembled from primed embryonic stem cells. Cell Stem Cell. 2022;29(6):962-972.e4, .

Mechanical regulation of early vertebrate embryogenesis

Valet M, Siggia ED, Brivanlou AH. Mechanical regulation of early vertebrate embryogenesis. Nature Reviews Molecular Cell Biology. 2022;23(3):169-184, .

Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions

Sáez M, Blassberg R, Camacho-Aguilar E, Siggia ED, Rand DA, Briscoe J. Statistically derived geometrical landscapes capture principles of decision-making dynamics during cell fate transitions. Cell Systems. 2022;13(1):12-28.e3, .

2021

Human neural tube morphogenesis in vitro by geometric constraints

Karzbrun E, Khankhel AH, Megale HC, Glasauer SMK, Wyle Y, Britton G, et al. Human neural tube morphogenesis in vitro by geometric constraints. Nature. 2021;599(7884):268-272, .

Geometry of gene regulatory dynamics

Rand DA, Raju A, Sáez M, Corson F, Siggia ED. Geometry of gene regulatory dynamics. Proceedings of the National Academy of Sciences of the United States of America. 2021;118(38).

Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport

Phan-Everson T, Etoc F, Li S, Khodursky S, Yoney A, Brivanlou AH, et al. Differential compartmentalization of BMP4/NOGGIN requires NOGGIN trans-epithelial transport. Developmental Cell. 2021;56(13):1930-1944.e5, .

2020

In vitro modeling of early mammalian embryogenesis

Hadjantonakis AK, Siggia ED, Simunovic M. In vitro modeling of early mammalian embryogenesis. Current Opinion in Biomedical Engineering. 2020;13:134-143, .