Publications
2010
Nucleosome-Depleted Regions in Cell-Cycle-Regulated Promoters Ensure Reliable Gene Expression in Every Cell Cycle
Bai L, Charvin G, Siggia E, Cross F. Nucleosome-Depleted Regions in Cell-Cycle-Regulated Promoters Ensure Reliable Gene Expression in Every Cell Cycle. Developmental Cell. 2010;18(4):544-555,.
Origin of irreversibility of cell cycle start in budding yeast
Charvin G, Oikonomou C, Siggia E, Cross F. Origin of irreversibility of cell cycle start in budding yeast. PLoS Biology. 2010;8(1).
2009
Scaling of BMP gradients in Xenopus embryos
François P, Vonica A, Brivanlou A, Siggia E. Scaling of BMP gradients in Xenopus embryos. Nature. 2009;461(7260).
Using DNA mechanics to predict in vitro nucleosome positions and formation energies
Morozov A, Fortney K, Gaykalova D, Studitsky V, Widom J, Siggia E. Using DNA mechanics to predict in vitro nucleosome positions and formation energies. Nucleic Acids Research. 2009;37(14):4707-4722,.
Forced periodic expression of G 1 cyclins phase-locks the budding yeast cell cycle
Charvin G, Cross F, Siggia E. Forced periodic expression of G 1 cyclins phase-locks the budding yeast cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 2009;106(16):6632-6637,.
Analysis of combinatorial cis-regulation in synthetic and genomic promoters
Gertz J, Siggia E, Cohen B. Analysis of combinatorial cis-regulation in synthetic and genomic promoters. Nature. 2009;457(7226):215-218,.
2008
Positive feedback of G1 cyclins ensures coherent cell cycle entry
Skotheim J, Di Talia S, Siggia E, Cross F. Positive feedback of G1 cyclins ensures coherent cell cycle entry. Nature. 2008;454(7202):291-296,.
A case study of evolutionary computation of biochemical adaptation
François P, Siggia E. A case study of evolutionary computation of biochemical adaptation. Physical Biology. 2008;5(2).
Sequence context affects the rate of short insertions and deletions in flies and primates
Tanay A, Siggia E. Sequence context affects the rate of short insertions and deletions in flies and primates. Genome Biology. 2008;9(2).
A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells
Charvin G, Cross F, Siggia E. A microfluidic device for temporally controlled gene expression and long-term fluorescent imaging in unperturbed dividing yeast cells. PLoS ONE. 2008;3(1).